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Therefore, preventing and treating vitamin B12 deficiency is good both for reducing the likelihood of parasite infestation and for helping an animal heal after a worm burden has been lifted

Decreased enzyme activity of MTHFR , combined with a diet lacking in folate, may result in a reduced breakdown of histamine

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Additionally, prolyl hydroxylase domain (PHD) inhibitors, such as the clinical drug Roxadustat (FG-4592), are capable of treating a variety of recalcitrant anaemiaincluding refractory anaemia, inflammatory anaemias, and chemotherapy-associated anaemiasby activating the HIF-2 axis [100]